Name: Dr. L. Böckmann
Telefon: +49-451-500 40432

Wissenschaftlicher Werdegang

Wissenschaftlicher Mitarbeiter
Leiter, Abteilung „Genomics & Transcriptomics“

Post-Doktorand
National Cancer Institute, Center for Cancer Research, NIH, Bethesda, USA

Promotion
DFG Graduiertenkolleg 1034
Georg-August-Universität Göttingen, Universitätsmedizin, Abt. Dermatologie, Venerologie und Allergologie (Prof. Emmert), Göttingen

Diplomstudiengang Biologie
Georg-August-Universität Göttingen

Università degli Studi di Roma „Tor Vergata“, Rom, Italien


Auszeichnungen

Fellows Award for Research Excellence (FARE) 2015
National Institutes of Health, Bethesda, USA

Travel Award „Outstanding Oral Presentation“
14th Center for Cancer Research Fellows and Young Investigators Colloquium, Frederick, USA

Finalist für Outstanding Postdoc of the Year Award 2014
Center for Cancer Research Fellows and Young Investigators, Shady Grove, USA

Reisestipendium
Deutschen Akademischen Austausch Dienstes (DAAD), Bonn

Teilnahmestipendium
Jahrestagung des German Academic International Network (GAIN), Boston, USA

Visiting Fellowship
National Cancer Institute, Bethesda, USA

Stipendium
DFG Graduiertenkolleg 1034, Göttingen


Aufgabenbereiche

Genomics, Transcriptomics und Zellkultur


Publikationen (Auszug)

Boeckmann L, Takahashi Y, Au WC, Mishra PK, Choy JS, Dawson AR, Szeto MY, WaybrightTJ, Heger C, McAndrew C, Goldsmith PK, Veenstra TD, Baker RE, Basrai MA. Phosphorylation of centromeric histone H3 variant regulates chromosome segregation in S. cerevisiae. Mol Biol Cell. 2013, Jun;24(12):2034-2044

Kuschal C, Thoms KM, Schubert S, Schäfer A, Boeckmann L, Schön MP / Editorial Board Member, Emmert S. Skin cancer in organ transplant recipients: Effects of immunosuppressive medications on DNA repair. Exp Dermatol. 2012 Jan;21(1):2-6.

Kuschal C, Thoms KM, Boeckmann L, Laspe P, Apel A, Schön MP, Emmert S. Cyclosporin A inhibits nukleotide excision repair via downregulation of the xeroderma pigmentosum group A and G proteins which is mediated by calcineurin inhibition. Exp Dermatol. 2011 Oct;20(10):795-9

Thoms KM, Kuschal C, Oetjen E, Mori T, Kobayashi N, Laspe P, Boeckmann L, Schön MP, Emmert S. Cyclosporin A, but not everolimus, inhibits DNA repair mediated by calcineurin: implications for tumorigenesis under immunosuppression. Exp Dermatol. 2011 Mar;20(3):232-6

Boeckmann L, Nickel AC, Kuschal C, Schaefer A, Thoms KM, Schön MP, Thomale J, Emmert S. Temozolomide chemoresistance heterogeneity in melanoma with different treatment regimens: DNA damage accumulation contribution. Melanoma Res. 2011 Jun;21(3):206-16

Knudsen S, Schardt A, Buhl T, Boeckmann L, Schön MP, Neumann C, Haenssle HA. Enhanced T cell activation by immature dendritic cells loaded with HSP70-expressing heat-killed melanoma cells. Exp Dermatol. 2010 Feb;19(2):108-16

Boeckmann L, Schirmer M, Rosenberger A, Struever D, Thoms KM, Gutzmer R, Has C, Kunz M, Kuschal C, Laspe P, Schoen MP, Brockmoeller J, Emmert S. Effect of DNA repair host factors on temozolomide or dacarbazine melanoma treatment in Caucasians. Pharmacogenet Genom. 2009 Oct;19(10):760-9

Schoof N, von Bonin F, König IR, Mössner R, Krüger U, Reich K, Berking C, Volkenandt M, Ziegler A, Böckmann L, Kuschal C, Thoms KM, Kube D, Emmert S. Distal and proximal interleukin (IL)-10 promoter polymorphisms associated with risk of cutaneous melanoma development: a case-control study. Genes Immun. 2009 Sep;10(6):586-90

Boeckmann L, Thoms KM, Gutzmer R, Has C, Kunz M, Kuschal C, Laspe P, Struever D, Emmert S. Modulation of the efficacy of temozolomide and dacarbazine melanoma treatment by DNA-repair factors in vivo and in vitro. Int J Clin Pharmacol Ther. 2009 Jan;47:33-5

Kuschal C, Thoms KM, Mori T, Kobayashi N, Boeckmann L, Laspe P, Emmert S. Cyclosporin A, but not everolimus, inhibits DNA repair in human fibroblasts and lymphoblasts. Int J Clin Pharmacol Ther. 2009 Jan;47:38-40